In Reply to: Not related? How do you know this? posted by J.R. on November 1, 2006 at 14:38:19:
most malignant cells require a complex support system to survive, ie angiogenesis, this expains the normal route of metastisis through lymphangenic or vasular routes. This also explains why different tumors have predictable routes of metastisis. For prostate this includes the pelvis and bones then lungs although that is often late stage disease. The trans rectal bx is not likely to violate any vasular or lymph routes. It is postualted that any tumor mass larger than 7mm will require its own blood supply for survival. General surgical practices are not likely to spread cancer. The exceptions to this are soft tissue sarcomas and the possible supressive nature the mother tumor may have on occult metastisis ( colo-rectal canccers). In truth, in soft tissue sarcoma is is usually a case of inadequate tissue margins in what apppears to be a slam dunk. I dont mean to be glib, but for those deciding on a prostate Bx, (and in this geriatric forum it may be many) surgical spread of the disease does not merrit concern.
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Follow Ups
- Re: Not related? How do you know this? - Zenos 18:38:21 11/01/06 (1)
- Many thanks. - J.R. 08:52:47 11/02/06 (0)